IHH Antibody
Product Specifications
Background
IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP) .
NCBI Gene ID
3549
Swiss Prot
Q14623
Accession Number
NP_002172
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IHH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IHH antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-052
Calculated Molecular Weight
45 kDa
Applications Notes
IHH antibody can be used for detection of IHH by ELISA at 1:312500. IHH antibody can be used for detection of IHH by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IHH
NCBI Official Name
Indian hedgehog
NCBI Organism
Homo sapiens
Background Reference 01
Kobune, M., (2004) Blood 104 (4), 1002-1009.
Other Product Names
IHH, BDA1, HHG2
Tested Applications
ELISA, WB, IHC
Protein ID
119392086
Physical Properties
Liquid
Curated Selection
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