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IHH Antibody

Product Specifications

Background

IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP) .

NCBI Gene ID

3549

Swiss Prot

Q14623

Accession Number

NP_002172

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IHH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer, Signal Transduction

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IHH antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Applications Notes

IHH antibody can be used for detection of IHH by ELISA at 1:312500. IHH antibody can be used for detection of IHH by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

IHH

NCBI Official Name

Indian hedgehog

NCBI Organism

Homo sapiens

Background Reference 01

Kobune, M., (2004) Blood 104 (4), 1002-1009.

Other Product Names

IHH, BDA1, HHG2

Tested Applications

ELISA, WB, IHC

Protein ID

119392086

Physical Properties

Liquid

Frequently Asked Questions

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