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MTUS1 Antibody

Product Specifications

Background

MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.

NCBI Gene ID

57509

Swiss Prot

Q9ULD2-3

Accession Number

NP_065800

Host

Rabbit

Reactivity

Human, Mouse, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTUS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MTUS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

48 kDa, 141 kDa, 136 kDa, 59 kDa

Applications Notes

MTUS1 antibody can be used for detection of MTUS1 by ELISA at 1:1562500. MTUS1 antibody can be used for detection of MTUS1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MTUS1

NCBI Official Name

Microtubule associated tumor suppressor 1

NCBI Organism

Homo sapiens

Background Reference 01

Nouet, S., (2004) J. Biol. Chem. 279 (28), 28989-28997.

Other Product Names

MTUS1, ATIP, DKFZp586D1519, DKFZp686F20243, FLJ14295, KIAA1288, MP44, MTSG1, ATBP, ICIS

Tested Applications

ELISA, WB

Protein ID

17865632

Physical Properties

Liquid

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