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NSMCE1 Antibody

Product Specifications

Background

NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.

NCBI Gene ID

197370

Swiss Prot

Q8WV22

Accession Number

NP_659547

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NSMCE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Immunology

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NSMCE1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

28 kDa

Applications Notes

NSMCE1 antibody can be used for detection of NSMCE1 by ELISA at 1:1562500. NSMCE1 antibody can be used for detection of NSMCE1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

NSMCE1

NCBI Official Name

Non-SMC element 1 homolog (S. cerevisiae)

NCBI Organism

Homo sapiens

Background Reference 01

Fujioka, Y., (2002) J. Biol. Chem. 277 (24), 21585-21591.

Other Product Names

NSMCE1, NSE1

Tested Applications

ELISA, WB

Protein ID

94721324

Physical Properties

Liquid

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