HIP2 Antibody
Product Specifications
Background
HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
NCBI Gene ID
3093
Swiss Prot
P61086
Accession Number
NP_005330
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HIP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-829
Calculated Molecular Weight
22 kDa
Applications Notes
HIP2 antibody can be used for detection of HIP2 by ELISA at 1:312500. HIP2 antibody can be used for detection of HIP2 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UBE2K
NCBI Official Name
Ubiquitin-conjugating enzyme E2K
NCBI Organism
Homo sapiens
Background Reference 01
Lee, S.J., (2001) FEBS Lett. 503 (1), 61-64.
Other Product Names
HIP2, HYPG, LIG, UBE2K, HIP2, UBC1, E2-25K
Tested Applications
ELISA, WB
Protein ID
4885417
Physical Properties
Liquid
Curated Selection
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