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RAPSN Antibody

Product Specifications

Background

RAPSN belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It is believed to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.This protein belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It is believed to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Two splice variants have been identified for this gene.

NCBI Gene ID

5913

Swiss Prot

Q13702-2

Accession Number

NP_116034

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RAPSN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Homeostasis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RAPSN antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

39 kDa, 46 kDa

Applications Notes

RAPSN antibody can be used for detection of RAPSN by ELISA at 1:312500. RAPSN antibody can be used for detection of RAPSN by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

RAPSN

NCBI Official Name

Receptor-associated protein of the synapse

NCBI Organism

Homo sapiens

Background Reference 01

Muller, J.S., (2004) Neuromuscul. Disord. 14 (11), 744-749.

Other Product Names

RAPSN, CMS1D, CMS1E, MGC3597, RAPSYN, RNF205

Tested Applications

ELISA, WB

Protein ID

38045928

Physical Properties

Liquid

Curated Selection

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