UBE2L3 Antibody
Product Specifications
Background
UBE2L3 (ubiquitin-conjugating enzyme E2L 3) Antibody The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
NCBI Gene ID
7332
Swiss Prot
P68036
Accession Number
NP_003338
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2L3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Homeostasis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UBE2L3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-824
Calculated Molecular Weight
17 kDa
Applications Notes
UBE2L3 antibody can be used for detection of UBE2L3 by ELISA at 1:62500. UBE2L3 antibody can be used for detection of UBE2L3 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UBE2L3
NCBI Official Name
Ubiquitin-conjugating enzyme E2L 3
NCBI Organism
Homo sapiens
Background Reference 01
Collins, J.E., Genome Biol. 5 (10), R84 (2004) .
Other Product Names
UBE2L3, E2-F1, L-UBC, UBCH7, UbcM4
Tested Applications
ELISA, WB
Protein ID
4507789
Physical Properties
Liquid
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