UBE2L3 Antibody

UBE2L3 (ubiquitin-conjugating enzyme E2L 3) Antibody The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UBE2L3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

UBE2L3 antibody can be used for detection of UBE2L3 by ELISA at 1:62500. UBE2L3 antibody can be used for detection of UBE2L3 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.