UPB1 Antibody
Product Specifications
Background
UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
NCBI Gene ID
51733
Swiss Prot
Q9UBR1
Accession Number
NP_057411
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Drosophila, Zebrafish, Arabidopsis, C. elegans
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UPB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UPB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-755
Calculated Molecular Weight
42 kDa
Applications Notes
UPB1 antibody can be used for detection of UPB1 by ELISA at 1:1562500. UPB1 antibody can be used for detection of UPB1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UPB1
NCBI Official Name
Ureidopropionase, beta
NCBI Organism
Homo sapiens
Background Reference 01
Van (2004) Hum. Mol. Genet. 13 (22), 2793-2801.
Other Product Names
UPB1, BUP1
Tested Applications
ELISA, WB
Protein ID
7706509
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
