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SEMG1 Antibody

Product Specifications

Background

SEMG1 is the predominant protein in semen. The secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

6406

Swiss Prot

P04279

Accession Number

NP_002998

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEMG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SEMG1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

51 kDa, 45 kDa

Applications Notes

SEMG1 antibody can be used for detection of SEMG1 by ELISA at 1:62500. SEMG1 antibody can be used for detection of SEMG1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SEMG1

NCBI Official Name

Semenogelin I

NCBI Organism

Homo sapiens

Background Reference 01

Hienonen, T., (2005) Cancer Res. 65 (11), 4607-4613.

Other Product Names

SEMG1, MGC14719, SEMG, SGI, CT103, dJ172H20.2

Tested Applications

ELISA, WB, IHC

Protein ID

4506883

Physical Properties

Liquid

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