DLAT Antibody
Product Specifications
Background
DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC; EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC; MIM 109720) show autoantibodies to DLAT.
NCBI Gene ID
1737
Swiss Prot
Q86YI5
Accession Number
NP_001922
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DLAT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DLAT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-681
Calculated Molecular Weight
71 kDa
Applications Notes
DLAT antibody can be used for detection of DLAT by ELISA at 1:312500. DLAT antibody can be used for detection of DLAT by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DLAT
NCBI Official Name
Dihydrolipoamide S-acetyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Head, R.A., (2005) Ann. Neurol. 58 (2), 234-241.
Other Product Names
DLAT, DLTA, PDC-E2, PDCE2
Tested Applications
ELISA, WB, IHC
Protein ID
31711992
Physical Properties
Liquid
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