ALOX15B Antibody
Product Specifications
Background
ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively.This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI Gene ID
247
Swiss Prot
O15296
Accession Number
NP_001132
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALOX15B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ALOX15B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-664
Calculated Molecular Weight
74 kDa, 73 kDa, 67 kDa
Applications Notes
ALOX15B antibody can be used for detection of ALOX15B by ELISA at 1:312500. ALOX15B antibody can be used for detection of ALOX15B by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ALOX15B
NCBI Official Name
Arachidonate 15-lipoxygenase, type B
NCBI Organism
Homo sapiens
Background Reference 01
Subbarayan, V., (2005) Neoplasia 7 (3), 280-293.
Other Product Names
ALOX15B, 15-LOX-2
Tested Applications
ELISA, WB
Protein ID
85067501
Physical Properties
Liquid
Curated Selection
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