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SLC22A1 Antibody

Product Specifications

Background

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A1 contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.

NCBI Gene ID

6580

Swiss Prot

O15245

Accession Number

NP_003048

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC22A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC22A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

61 kDa, 56 kDa

Applications Notes

SLC22A1 antibody can be used for detection of SLC22A1 by ELISA at 1:62500. SLC22A1 antibody can be used for detection of SLC22A1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SLC22A1

NCBI Official Name

Solute carrier family 22 (organic cation transporter), member 1

NCBI Organism

Homo sapiens

Background Reference 01

Bourdet, D.L., (2005) J. Pharmacol. Exp. Ther. 315 (3), 1288-1297.

Other Product Names

SLC22A1, HOCT1, OCT1, oct1_cds

Tested Applications

ELISA, WB, IHC

Protein ID

4506999

Physical Properties

Liquid

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