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SLC13A3 Antibody

Product Specifications

Background

Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.

NCBI Gene ID

64849

Swiss Prot

Q8WWT9

Accession Number

NP_001011554

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC13A3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC13A3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=29-575

Calculated Molecular Weight

61 kDa, 67 kDa

Applications Notes

SLC13A3 antibody can be used for detection of SLC13A3 by ELISA at 1:312500. SLC13A3 antibody can be used for detection of SLC13A3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SLC13A3

NCBI Official Name

Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

NCBI Organism

Homo sapiens

Background Reference 01

Bai, X., (2006) J. Cell. Physiol. 206 (3), 821-830.

Other Product Names

SLC13A3, NADC3, SDCT2

Tested Applications

ELISA, WB, IHC

Protein ID

58761541

Physical Properties

Liquid

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