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PON1 Antibody

Product Specifications

Background

PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

NCBI Gene ID

5444

Swiss Prot

P27169

Accession Number

NP_000437

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PON1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PON1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

39 kDa

Applications Notes

PON1 antibody can be used for detection of PON1 by ELISA at 1:1562500. PON1 antibody can be used for detection of PON1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PON1

NCBI Official Name

Paraoxonase 1

NCBI Organism

Homo sapiens

Background Reference 01

Rosenblat, M., (2006) J. Biol. Chem. 281 (11), 7657-7665.

Other Product Names

PON1, ESA, PON, MVCD5

Tested Applications

ELISA, WB

Protein ID

19923106

Physical Properties

Liquid

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