SLC12A1 Antibody
Product Specifications
Background
The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene.
NCBI Gene ID
6557
Swiss Prot
Q8IUN5
Accession Number
AAH40138
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC12A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC12A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-559
Calculated Molecular Weight
47 kDa, 121 kDa
Applications Notes
SLC12A1 antibody can be used for detection of SLC12A1 by ELISA at 1:312500. SLC12A1 antibody can be used for detection of SLC12A1 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SLC12A1
NCBI Official Name
Solute carrier family 12 (sodium/potassium/chloride transporter), member 1
NCBI Organism
Homo sapiens
Other Product Names
SLC12A1, BSC1, MGC48843, NKCC2
Tested Applications
ELISA, WB, IHC
Protein ID
25304083
Physical Properties
Liquid
Curated Selection
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