THEX1 Antibody
Product Specifications
Background
THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi) .
NCBI Gene ID
90459
Swiss Prot
Q8IV48
Accession Number
NP_699163
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human THEX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store THEX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-513
Calculated Molecular Weight
40 kDa
Applications Notes
THEX1 antibody can be used for detection of THEX1 by ELISA at 1:312500. THEX1 antibody can be used for detection of THEX1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ERI1
NCBI Official Name
Exoribonuclease 1
NCBI Organism
Homo sapiens
Background Reference 01
Kupsco, J.M., (2006) RNA 12 (12), 2103-2117.
Other Product Names
THEX1, 3'HEXO, MGC35395, HEXO, THEX1
Tested Applications
ELISA, WB
Protein ID
31543184
Physical Properties
Liquid
Curated Selection
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