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CPSF3 Antibody

Product Specifications

Background

CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition.

NCBI Gene ID

51692

Swiss Prot

Q9UKF6

Accession Number

NP_057291

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

75 kDa

Applications Notes

CPSF3 antibody can be used for detection of CPSF3 by ELISA at 1:62500. CPSF3 antibody can be used for detection of CPSF3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CPSF3

NCBI Official Name

Cleavage and polyadenylation specific factor 3, 73kDa

NCBI Organism

Homo sapiens

Background Reference 01

Calzado, M.A., (2004) J. Virol. 78 (13), 6846-6854.

Other Product Names

CPSF3, CPSF73, CPSF-73

Tested Applications

ELISA, WB, IHC

Protein ID

7706427

Physical Properties

Liquid

Frequently Asked Questions

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