CPSF3 Antibody
Product Specifications
Background
CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition.
NCBI Gene ID
51692
Swiss Prot
Q9UKF6
Accession Number
NP_057291
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
75 kDa
Applications Notes
CPSF3 antibody can be used for detection of CPSF3 by ELISA at 1:312500. CPSF3 antibody can be used for detection of CPSF3 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CPSF3
NCBI Official Name
Cleavage and polyadenylation specific factor 3, 73kDa
NCBI Organism
Homo sapiens
Background Reference 01
Calzado, M.A., (2004) J. Virol. 78 (13), 6846-6854.
Other Product Names
CPSF3, CPSF73, CPSF-73
Tested Applications
ELISA, WB
Protein ID
7706427
Physical Properties
Liquid
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