CPSF1 Antibody
Product Specifications
Background
CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
NCBI Gene ID
29894
Swiss Prot
Q10570
Accession Number
NP_037423
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-411
Calculated Molecular Weight
161 kDa
Applications Notes
CPSF1 antibody can be used for detection of CPSF1 by ELISA at 1:62500. CPSF1 antibody can be used for detection of CPSF1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CPSF1
NCBI Official Name
Cleavage and polyadenylation specific factor 1, 160kDa
NCBI Organism
Homo sapiens
Background Reference 01
Beausoleil, S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135.
Other Product Names
CPSF1, CPSF160, HSU37012, P/cl.18
Tested Applications
ELISA, WB
Protein ID
56676371
Physical Properties
Liquid
Curated Selection
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