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IRAK3 Antibody

Product Specifications

Background

IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

NCBI Gene ID

11213

Swiss Prot

Q9Y616

Accession Number

NP_009130

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRAK3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRAK3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

66 kDa

Applications Notes

IRAK3 antibody can be used for detection of IRAK3 by ELISA at 1:62500. IRAK3 antibody can be used for detection of IRAK3 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

IRAK3

NCBI Official Name

Interleukin-1 receptor-associated kinase 3

NCBI Organism

Homo sapiens

Background Reference 01

Del (2005) J. Immunol. 174 (5), 3032-3040.

Other Product Names

IRAK3, ASRT5, IRAKM

Tested Applications

ELISA, WB

Protein ID

216547519

Physical Properties

Liquid

Frequently Asked Questions

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