IRAK3 Antibody
Product Specifications
Background
IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
NCBI Gene ID
11213
Swiss Prot
Q9Y616
Accession Number
NP_009130
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRAK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRAK3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-402
Calculated Molecular Weight
66 kDa
Applications Notes
IRAK3 antibody can be used for detection of IRAK3 by ELISA at 1:62500. IRAK3 antibody can be used for detection of IRAK3 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IRAK3
NCBI Official Name
Interleukin-1 receptor-associated kinase 3
NCBI Organism
Homo sapiens
Background Reference 01
Del (2005) J. Immunol. 174 (5), 3032-3040.
Other Product Names
IRAK3, ASRT5, IRAKM
Tested Applications
ELISA, WB
Protein ID
216547519
Physical Properties
Liquid
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