ZRSR2 Antibody
Product Specifications
Background
ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant.
NCBI Gene ID
8233
Swiss Prot
Q15696
Accession Number
NP_005080
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZRSR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZRSR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-347
Calculated Molecular Weight
53 kDa
Applications Notes
ZRSR2 antibody can be used for detection of ZRSR2 by ELISA at 1:62500. ZRSR2 antibody can be used for detection of ZRSR2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ZRSR2
NCBI Official Name
Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
NCBI Organism
Homo sapiens
Background Reference 01
Will, C.L., (2004) RNA 10 (6), 929-941.
Other Product Names
ZRSR2, URP, U2AF1L2, U2AF1RS2, U2AF1-RS2
Tested Applications
ELISA, WB, IHC
Protein ID
4827046
Physical Properties
Liquid
Curated Selection
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