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PRKRA Antibody

Product Specifications

Background

PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA) .

NCBI Gene ID

8575

Swiss Prot

O75569

Accession Number

NP_003681

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRKRA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Immunology

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PRKRA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

34 kDa

Applications Notes

PRKRA antibody can be used for detection of PRKRA by ELISA at 1:62500. PRKRA antibody can be used for detection of PRKRA by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PRKRA

NCBI Official Name

Protein kinase, interferon-inducible double stranded RNA dependent activator

NCBI Organism

Homo sapiens

Background Reference 01

Lee, Y., (2006) EMBO J. 25 (3), 522-532.

Other Product Names

PRKRA, RAX, PACT, DYT16, HSD14

Tested Applications

ELISA, WB, IHC

Protein ID

4505581

Physical Properties

Liquid

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