XPO1 Antibody

XPO1 mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store XPO1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

XPO1 antibody can be used for detection of XPO1 by ELISA at 1:62500. XPO1 antibody can be used for detection of XPO1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.