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RBM9 Antibody

Product Specifications

Background

RBM9 is a RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

23543

Swiss Prot

O43251

Accession Number

NP_001026865

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBM9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RBM9 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=29-264

Calculated Molecular Weight

40 kDa

Applications Notes

RBM9 antibody can be used for detection of RBM9 by ELISA at 1:312500. RBM9 antibody can be used for detection of RBM9 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

RBFOX2

NCBI Official Name

RNA binding protein, fox-1 homolog (C. elegans) 2

NCBI Organism

Homo sapiens

Background Reference 01

Yang, G., (2008) Blood 111 (1), 392-401.

Other Product Names

RBM9, Fox-2, HNRBP2, HRNBP2, RTA, dJ106I20.3, fxh, FOX2, RBM9

Tested Applications

ELISA, WB

Protein ID

72534682

Physical Properties

Liquid

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