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TCFAP2C Antibody

Product Specifications

Background

Tcfap2c is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. Tcfap2c binds to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

NCBI Gene ID

21420

Swiss Prot

Q61312

Accession Number

NP_033361

Host

Rabbit

Reactivity

Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse TCFAP2C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by protein A chromatography method.

Positive Control

SP2/0 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCFAP2C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

49 kDa

Applications Notes

TCFAP2C antibody can be used for detection of TCFAP2C by ELISA at 1:1562500. TCFAP2C antibody can be used for detection of TCFAP2C by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

Tfap2c

NCBI Official Name

Transcription factor AP-2, gamma

NCBI Organism

Mus musculus

Background Reference 01

Jager, R., et al., (2005) Breast Cancer Res. Treat. 90 (3), 273-280.

Other Product Names

TCFAP2C, Stra2, Ap-2.2, Tcfap2c, AA409384, AP2gamma

Tested Applications

ELISA, WB

Protein ID

228008347

Physical Properties

Liquid

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