TCFAP2C Antibody
Product Specifications
Background
Tcfap2c is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. Tcfap2c binds to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
NCBI Gene ID
21420
Swiss Prot
Q61312
Accession Number
NP_033361
Host
Rabbit
Reactivity
Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse TCFAP2C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
SP2/0 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCFAP2C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
49 kDa
Applications Notes
TCFAP2C antibody can be used for detection of TCFAP2C by ELISA at 1:1562500. TCFAP2C antibody can be used for detection of TCFAP2C by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
Tfap2c
NCBI Official Name
Transcription factor AP-2, gamma
NCBI Organism
Mus musculus
Background Reference 01
Jager, R., et al., (2005) Breast Cancer Res. Treat. 90 (3), 273-280.
Other Product Names
TCFAP2C, Stra2, Ap-2.2, Tcfap2c, AA409384, AP2gamma
Tested Applications
ELISA, WB
Protein ID
228008347
Physical Properties
Liquid
Curated Selection
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