GLIS3 Antibody
Product Specifications
Background
GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH) .
NCBI Gene ID
169792
Swiss Prot
Q1PHJ8
Accession Number
NP_689842
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GLIS3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GLIS3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
84 kDa, 100 kDa
Applications Notes
GLIS3 antibody can be used for detection of GLIS3 by ELISA at 1:62500. GLIS3 antibody can be used for detection of GLIS3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GLIS3
NCBI Official Name
GLIS family zinc finger 3
NCBI Organism
Homo sapiens
Background Reference 01
Kim, Y.S., (2003) Nucleic Acids Res. 31 (19), 5513-5525.
Other Product Names
GLIS3, ZNF515
Tested Applications
ELISA, WB
Protein ID
109637782
Physical Properties
Liquid
Frequently Asked Questions
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