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HMBOX1 Antibody

Product Specifications

Background

HMBOX1 is located at the boundary of 8p12.3 and 8p21.1. HMBOX1 proteins are highly conserved in human, mouse, rat, chicken and Xenopus laevis. Functional HMBOX1::EGFP (enhanced green fluorescent protein) fusion protein revealed that HMBOX1 accumulated more in cytoplasm than in nucleus. HMBOX1 is a transcription repressor. Human HMBOX1 is widely expressed in 18 tissues, and it is highly expressed in pancreas. Hmbox1 is widely expressed in mouse pancreas and the expression of this gene can also be detected in pallium, hippocampus and hypothalamus.

NCBI Gene ID

79618

Swiss Prot

Q6NT76

Accession Number

NP_078843

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HMBOX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HMBOX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=29-090

Calculated Molecular Weight

47 kDa

Applications Notes

HMBOX1 antibody can be used for detection of HMBOX1 by ELISA at 1:312500. HMBOX1 antibody can be used for detection of HMBOX1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HMBOX1

NCBI Official Name

Homeobox containing 1

NCBI Organism

Homo sapiens

Background Reference 01

Strausberg, R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903.

Other Product Names

HMBOX1, HOT1, PBHNF, HNF1LA

Tested Applications

ELISA, WB

Protein ID

47059040

Physical Properties

Liquid

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