HOXB4 Antibody
Product Specifications
Background
HOXB4 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. The protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
NCBI Gene ID
3214
Swiss Prot
P17483
Accession Number
NP_076920
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXB4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HOXB4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
28 kDa, 34 kDa, 28 kDa
Applications Notes
HOXB4 antibody can be used for detection of HOXB4 by ELISA at 1:62500. HOXB4 antibody can be used for detection of HOXB4 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HOXB4
NCBI Official Name
Homeobox B4
NCBI Organism
Homo sapiens
Background Reference 01
Pineault, N., (2004) Mol. Cell. Biol. 24 (5), 1907-1917.
Other Product Names
HOXB4, HOX-2.6, HOX2, HOX2F
Tested Applications
ELISA, WB
Protein ID
13273315
Physical Properties
Liquid
Curated Selection
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