KLHL3 Antibody
Product Specifications
Background
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
NCBI Gene ID
26249
Swiss Prot
Q9UH77
Accession Number
NP_059111
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLHL3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KLHL3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-037
Calculated Molecular Weight
65 kDa
Applications Notes
KLHL3 antibody can be used for detection of KLHL3 by ELISA at 1:62500. KLHL3 antibody can be used for detection of KLHL3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KLHL3
NCBI Official Name
Kelch-like family member 3
NCBI Organism
Homo sapiens
Background Reference 01
Lai, F., et al., (2000) Genomics 66 (1), 65-75.
Other Product Names
KLHL3, PHA2D
Tested Applications
ELISA, WB
Protein ID
166235129
Physical Properties
Liquid
Curated Selection
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