ERG Ion Channel 2 Antibody
Product Specifications
Background
ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.
NCBI Gene ID
51290
Swiss Prot
Q96RQ1
Accession Number
NP_057654
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERG Ion Channel 2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ERG Ion Channel 2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-034
Calculated Molecular Weight
43 kDa
Applications Notes
ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by ELISA at 1:62500. ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ERGIC2
NCBI Official Name
ERGIC and golgi 2
NCBI Organism
Homo sapiens
Background Reference 01
Thomas J. Nelson, et al., (2007) J Biol Chem 282:31238.
Other Product Names
ERGIon Channel2, PTX1, CDA14, Erv41, cd002
Tested Applications
ELISA, WB
Protein ID
50959176
Physical Properties
Liquid
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