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ERG Ion Channel 2 Antibody

Product Specifications

Background

ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.

NCBI Gene ID

51290

Swiss Prot

Q96RQ1

Accession Number

NP_057654

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERG Ion Channel 2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ERG Ion Channel 2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

43 kDa

Applications Notes

ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by ELISA at 1:62500. ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ERGIC2

NCBI Official Name

ERGIC and golgi 2

NCBI Organism

Homo sapiens

Background Reference 01

Thomas J. Nelson, et al., (2007) J Biol Chem 282:31238.

Other Product Names

ERGIon Channel2, PTX1, CDA14, Erv41, cd002

Tested Applications

ELISA, WB

Protein ID

50959176

Physical Properties

Liquid

Frequently Asked Questions

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