SART3 Antibody
Product Specifications
Background
SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
NCBI Gene ID
9733
Swiss Prot
Q15020-2
Accession Number
AAK69347
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SART3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SART3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-012
Calculated Molecular Weight
40 kDa, 110 kDa
Applications Notes
SART3 antibody can be used for detection of SART3 by ELISA at 1:62500. SART3 antibody can be used for detection of SART3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SART3
NCBI Official Name
Squamous cell carcinoma antigen recognized by T cells 3
NCBI Organism
Homo sapiens
Background Reference 01
Liu, Y., (2002) J. Biol. Chem. 277 (26), 23854-23863.
Other Product Names
SART3, P100, p110, DSAP1, TIP110, p110 (nrb), RP11-13G14
Tested Applications
ELISA, WB, IHC
Protein ID
14579643
Physical Properties
Liquid
Curated Selection
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