VSX1 Antibody
Product Specifications
Background
VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
30813
Swiss Prot
Q9NZR4-2
Accession Number
NP_955457
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VSX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store VSX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
25 kDa
Applications Notes
VSX1 antibody can be used for detection of VSX1 by ELISA at 1:12500. VSX1 antibody can be used for detection of VSX1 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
VSX1
NCBI Official Name
Visual system homeobox 1
NCBI Organism
Homo sapiens
Background Reference 01
Valleix, S., et al., (2006) Invest. Ophthalmol. Vis. Sci. 47 (1), 48-54.
Other Product Names
VSX1, PPD, KTCN, PPCD, RINX, KTCN1, PPCD1, CAASDS
Tested Applications
ELISA, WB
Protein ID
40806216
Physical Properties
Liquid
Curated Selection
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