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CNOT7 Antibody

Product Specifications

Background

CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

NCBI Gene ID

29883

Swiss Prot

Q9UIV1

Accession Number

NP_037486

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Zebrafish

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CNOT7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CNOT7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=28-998

Calculated Molecular Weight

30 kDa, 28 kDa

Applications Notes

CNOT7 antibody can be used for detection of CNOT7 by ELISA at 1:312500. CNOT7 antibody can be used for detection of CNOT7 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CNOT7

NCBI Official Name

CCR4-NOT transcription complex, subunit 7

NCBI Organism

Homo sapiens

Background Reference 01

Kimura, K., (2006) Genome Res. 16 (1), 55-65.

Other Product Names

CNOT7, CAF1, Caf1a, hCAF-1

Tested Applications

ELISA, WB

Protein ID

85067507

Physical Properties

Liquid

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