TRIM32 Antibody
Product Specifications
Background
TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
NCBI Gene ID
22954
Swiss Prot
Q13049
Accession Number
NP_036342
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM32.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRIM32 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-983
Calculated Molecular Weight
72 kDa
Applications Notes
TRIM32 antibody can be used for detection of TRIM32 by ELISA at 1:62500. TRIM32 antibody can be used for detection of TRIM32 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TRIM32
NCBI Official Name
Tripartite motif containing 32
NCBI Organism
Homo sapiens
Background Reference 01
Chiang, A.P., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (16), 6287-6292.
Other Product Names
TRIM32, HT2A, BBS11, TATIP, LGMD2H
Tested Applications
ELISA, WB
Protein ID
153792582
Physical Properties
Liquid
Curated Selection
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