TFEB Antibody
Product Specifications
Background
TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6;11) (p21; q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
NCBI Gene ID
7942
Swiss Prot
P19484
Accession Number
NP_009093
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFEB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TFEB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-949
Calculated Molecular Weight
53 kDa
Applications Notes
TFEB antibody can be used for detection of TFEB by ELISA at 1:312500. TFEB antibody can be used for detection of TFEB by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TFEB
NCBI Official Name
Transcription factor EB
NCBI Organism
Homo sapiens
Background Reference 01
Argani, P., et al., (2005) Am. J. Surg. Pathol. 29 (2), 230-240.
Other Product Names
TFEB, TCFEB, BHLHE35, ALPHATFEB
Tested Applications
ELISA, WB
Protein ID
24307933
Physical Properties
Liquid
Curated Selection
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