TAF1C Antibody
Product Specifications
Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF.
NCBI Gene ID
9013
Swiss Prot
Q15572-2
Accession Number
NP_647610
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAF1C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TAF1C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
85 kDa, 95 kDa
Applications Notes
TAF1C antibody can be used for detection of TAF1C by ELISA at 1:12500. TAF1C antibody can be used for detection of TAF1C by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TAF1C
NCBI Official Name
TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa
NCBI Organism
Homo sapiens
Background Reference 01
Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65.
Other Product Names
TAF1C, SL1, TAFI95, TAFI110, MGC:39976
Tested Applications
ELISA, WB
Protein ID
341926265
Physical Properties
Liquid
Frequently Asked Questions
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