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TAF1C Antibody

Product Specifications

Background

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF.

NCBI Gene ID

9013

Swiss Prot

Q15572-2

Accession Number

NP_647610

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAF1C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TAF1C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

85 kDa, 95 kDa

Applications Notes

TAF1C antibody can be used for detection of TAF1C by ELISA at 1:12500. TAF1C antibody can be used for detection of TAF1C by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TAF1C

NCBI Official Name

TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa

NCBI Organism

Homo sapiens

Background Reference 01

Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65.

Other Product Names

TAF1C, SL1, TAFI95, TAFI110, MGC:39976

Tested Applications

ELISA, WB

Protein ID

341926265

Physical Properties

Liquid

Frequently Asked Questions

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