TP53BP2 Antibody
Product Specifications
Background
TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. TP53BP2 contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. TP53BP2 is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family.
NCBI Gene ID
7159
Swiss Prot
Q13625
Accession Number
NP_001026855
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP53BP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP53BP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
124 kDa, 111 kDa
Applications Notes
TP53BP2 antibody can be used for detection of TP53BP2 by ELISA at 1:1562500. TP53BP2 antibody can be used for detection of TP53BP2 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TP53BP2
NCBI Official Name
Tumor protein p53 binding protein, 2
NCBI Organism
Homo sapiens
Background Reference 01
Ju, H., et al., (2005) Int. J. Cancer 117 (6), 957-960.
Other Product Names
TP53BP2, BBP, 53BP2, ASPP2, P53BP2, PPP1R13A
Tested Applications
ELISA, WB
Protein ID
112799849
Physical Properties
Liquid
Frequently Asked Questions
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