CIR Antibody
Product Specifications
Background
CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC) . CIR is also required for RBPSUH-mediated repression of transcription.
NCBI Gene ID
9541
Swiss Prot
Q86X95
Accession Number
NP_004873
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CIR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CIR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
52 kDa
Applications Notes
CIR antibody can be used for detection of CIR by ELISA at 1:62500. CIR antibody can be used for detection of CIR by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CIR1
NCBI Official Name
Corepressor interacting with RBPJ, 1
NCBI Organism
Homo sapiens
Background Reference 01
Maita, H., (2005) Exp. Cell Res. 303 (2), 375-387.
Other Product Names
CIR, CIR
Tested Applications
ELISA, WB
Protein ID
40068059
Physical Properties
Liquid
Curated Selection
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