WDR39 Antibody
Product Specifications
Background
WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
NCBI Gene ID
9391
Swiss Prot
O76071
Accession Number
NP_004795
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR39.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store WDR39 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
38 kDa
Applications Notes
WDR39 antibody can be used for detection of WDR39 by ELISA at 1:312500. WDR39 antibody can be used for detection of WDR39 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CIAO1
NCBI Official Name
Cytosolic iron-sulfur assembly component 1
NCBI Organism
Homo sapiens
Background Reference 01
Johnstone, R.W., et al., (1998) J. Biol. Chem. 273 (18), 10880-10887.
Other Product Names
WDR39, CIA1, WDR39
Tested Applications
ELISA, WB
Protein ID
4757988
Physical Properties
Liquid
Curated Selection
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