CREG1 Antibody
Product Specifications
Background
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
NCBI Gene ID
8804
Swiss Prot
O75629
Accession Number
NP_003842
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREG1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CREG1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
24 kDa
Applications Notes
CREG1 antibody can be used for detection of CREG1 by ELISA at 1:1562500. CREG1 antibody can be used for detection of CREG1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CREG1
NCBI Official Name
Cellular repressor of E1A-stimulated genes 1
NCBI Organism
Homo sapiens
Background Reference 01
Sacher, M., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18326-18331.
Other Product Names
CREG1, CREG
Tested Applications
ELISA, WB
Protein ID
4503037
Physical Properties
Liquid
Curated Selection
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