ZNF76 Antibody
Product Specifications
Background
ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.
NCBI Gene ID
7629
Swiss Prot
P36508
Accession Number
NP_003418
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF76.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZNF76 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
62 kDa
Applications Notes
ZNF76 antibody can be used for detection of ZNF76 by ELISA at 1:312500. ZNF76 antibody can be used for detection of ZNF76 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ZNF76
NCBI Official Name
Zinc finger protein 76
NCBI Organism
Homo sapiens
Background Reference 01
Zheng, G. (2006) Biochem. Biophys. Res. Commun. 339 (4), 1069-1075.
Other Product Names
ZNF76, ZNF523, Zfp523, D6S229E
Tested Applications
ELISA, WB
Protein ID
21361146
Physical Properties
Liquid
Curated Selection
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