TCF3 Antibody
Product Specifications
Background
TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
NCBI Gene ID
6929
Swiss Prot
P15923
Accession Number
NP_003191
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-832
Calculated Molecular Weight
68 kDa
Applications Notes
TCF3 antibody can be used for detection of TCF3 by ELISA at 1:1562500. TCF3 antibody can be used for detection of TCF3 by western blot at 0.31 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TCF3
NCBI Official Name
Transcription factor 3
NCBI Organism
Homo sapiens
Background Reference 01
Maruyama, K. (2005) J. Biol. Chem. 280 (41), 34577-34589.
Other Product Names
TCF3, E2A, E47, ITF1, VDIR, TCF-3, bHLHb21
Tested Applications
ELISA, WB
Protein ID
27777636
Physical Properties
Liquid
Curated Selection
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