MNAT1 Antibody
Product Specifications
Background
Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK) . CAK is a multisubunit protein that includes CDK7, cyclin H, and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK) . CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH; MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.
NCBI Gene ID
4331
Swiss Prot
P51948
Accession Number
NP_002422
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MNAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cell Cycle, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MNAT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
36 kDa
Applications Notes
MNAT1 antibody can be used for detection of MNAT1 by ELISA at 1:312500. MNAT1 antibody can be used for detection of MNAT1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MNAT1
NCBI Official Name
MNAT CDK-activating kinase assembly factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Zhou, M., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (22), 12666-12671.
Other Product Names
MNAT1, MAT1, TFB3, CAP35, RNF66
Tested Applications
ELISA, WB
Protein ID
4505225
Physical Properties
Liquid
Frequently Asked Questions
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