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MNAT1 Antibody

Product Specifications

Background

Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK) . CAK is a multisubunit protein that includes CDK7, cyclin H, and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK) . CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH; MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.

NCBI Gene ID

4331

Swiss Prot

P51948

Accession Number

NP_002422

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MNAT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MNAT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=28-804

Calculated Molecular Weight

36 kDa

Applications Notes

MNAT1 antibody can be used for detection of MNAT1 by ELISA at 1:312500. MNAT1 antibody can be used for detection of MNAT1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MNAT1

NCBI Official Name

MNAT CDK-activating kinase assembly factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Zhou, M., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (22), 12666-12671.

Other Product Names

MNAT1, MAT1, TFB3, CAP35, RNF66

Tested Applications

ELISA, WB

Protein ID

4505225

Physical Properties

Liquid

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