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DR1 Antibody

Product Specifications

Background

DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif

NCBI Gene ID

1810

Swiss Prot

Q01658

Accession Number

NP_001929

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Zebrafish

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DR1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

19 kDa

Applications Notes

DR1 antibody can be used for detection of DR1 by ELISA at 1:62500. DR1 antibody can be used for detection of DR1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

DR1

NCBI Official Name

Down-regulator of transcription 1, TBP-binding (negative cofactor 2)

NCBI Organism

Homo sapiens

Background Reference 01

Gilfillan, S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230.

Other Product Names

DR1, NC2, NC2-BETA

Tested Applications

ELISA, WB

Protein ID

4503381

Physical Properties

Liquid

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