DR1 Antibody
Product Specifications
Background
DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
NCBI Gene ID
1810
Swiss Prot
Q01658
Accession Number
NP_001929
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DR1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
19 kDa
Applications Notes
DR1 antibody can be used for detection of DR1 by ELISA at 1:62500. DR1 antibody can be used for detection of DR1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DR1
NCBI Official Name
Down-regulator of transcription 1, TBP-binding (negative cofactor 2)
NCBI Organism
Homo sapiens
Background Reference 01
Gilfillan, S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230.
Other Product Names
DR1, NC2, NC2-BETA
Tested Applications
ELISA, WB
Protein ID
4503381
Physical Properties
Liquid
Curated Selection
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