TWIST1 Antibody
Product Specifications
Background
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation.TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
NCBI Gene ID
7291
Swiss Prot
Q15672
Accession Number
NP_000465
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TWIST1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TWIST1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
21 kDa
Applications Notes
TWIST1 antibody can be used for detection of TWIST1 by ELISA at 1:1562500. TWIST1 antibody can be used for detection of TWIST1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TWIST1
NCBI Official Name
Twist family bHLH transcription factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Reinhold, M.I., et al., (2006) J. Biol. Chem. 281 (3), 1381-1388.
Other Product Names
TWIST1, CRS, SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38
Tested Applications
ELISA, WB
Protein ID
4507741
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
