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TGFB1 Antibody

Product Specifications

Background

Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

NCBI Gene ID

21803

Swiss Prot

P04202

Accession Number

NP_035707

Host

Rabbit

Reactivity

Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse TGFB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

SP2/0 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TGFB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

43 kDa

Applications Notes

TGFB1 antibody can be used for detection of TGFB1 by ELISA at 1:1562500. TGFB1 antibody can be used for detection of TGFB1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TGFB1

NCBI Official Name

Transforming growth factor, beta 1

NCBI Organism

Mus musculus

Background Reference 01

Cheon, S.S., (2006) FASEB J. 20 (6), 692-701.

Other Product Names

TGFB1, Tgfb, Tgfb-1, TGFbeta1, TGF-beta1

Tested Applications

ELISA, WB

Protein ID

6755775

Physical Properties

Liquid

Frequently Asked Questions

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