DDX46 Antibody

DDX46 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX46 is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDX46 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

DDX46 antibody can be used for detection of DDX46 by ELISA at 1:12500. DDX46 antibody can be used for detection of DDX46 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.