DDX46 Antibody
Product Specifications
Background
DDX46 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX46 is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
NCBI Gene ID
9879
Swiss Prot
Q7L014
Accession Number
NP_055644
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX46.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDX46 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
113 kDa
Applications Notes
DDX46 antibody can be used for detection of DDX46 by ELISA at 1:12500. DDX46 antibody can be used for detection of DDX46 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DDX46
NCBI Official Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
NCBI Organism
Homo sapiens
Background Reference 01
Xu, Y.Z., et al., (2004) EMBO J. 23 (2), 376-385.
Other Product Names
DDX46, Prp5, PRPF5
Tested Applications
ELISA, WB
Protein ID
41327773
Physical Properties
Liquid
Curated Selection
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