YAF2 Antibody
Product Specifications
Background
Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.
NCBI Gene ID
67057
Swiss Prot
Q99LW6
Accession Number
NP_077151
Host
Rabbit
Reactivity
Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse YAF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1282 - 3T3 (NIH) Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store YAF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
20 kDa
Applications Notes
YAF2 antibody can be used for detection of YAF2 by ELISA at 1:312500. YAF2 antibody can be used for detection of YAF2 by western blot at 0.2 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
YAF2
NCBI Official Name
YY1 associated factor 2
NCBI Organism
Mus musculus
Background Reference 01
Kaneko, T., Gene 315, 183-192 (2003) .
Other Product Names
YAF2, 2810021M11Rik
Tested Applications
ELISA, WB
Protein ID
40254385
Physical Properties
Liquid
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