IRF5 Antibody
Product Specifications
Background
The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
NCBI Gene ID
27056
Swiss Prot
P56477
Accession Number
NP_036187
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse IRF5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1369 - Human Lymph node Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRF5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-629
Calculated Molecular Weight
55 kDa
Applications Notes
IRF5 antibody can be used for detection of IRF5 by ELISA at 1:62500. IRF5 antibody can be used for detection of IRF5 by western blot at 0.15 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IRF5
NCBI Official Name
Interferon regulatory factor 5
NCBI Organism
Mus musculus
Background Reference 01
Takaoka, A., et al., (2005) Nature 434 (7030), 243-249.
Other Product Names
IRF5, mirf5, AW491843
Tested Applications
ELISA, WB
Protein ID
6754368
Physical Properties
Liquid
Curated Selection
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