SREBF1 Antibody
Product Specifications
Background
Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') . Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3') . Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.
NCBI Gene ID
20787
Swiss Prot
Q9WTN3
Accession Number
NP_035610
Host
Rabbit
Reactivity
Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse SREBF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
SP2/0 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SREBF1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
125 kDa
Applications Notes
SREBF1 antibody can be used for detection of SREBF1 by ELISA at 1:62500. SREBF1 antibody can be used for detection of SREBF1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SREBF1
NCBI Official Name
Sterol regulatory element binding transcription factor 1
NCBI Organism
Mus musculus
Background Reference 01
Briancon, N. (2006) EMBO J. 25 (6), 1253-1262.
Other Product Names
SREBF1, ADD1, ADD-1, SREBP1, bHLHd1, SREBP-1, SREBP1c, SREBP-1a, SREBP-1c, D630008H06
Tested Applications
ELISA, WB
Protein ID
27753981
Physical Properties
Liquid
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